THROMBOLYTIC THERAPY AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION

Rudakova Lyudmila Efimovna, Candidate of medical sciences, associate professor, sub-department of internal diseases, Medical Institute, Penza State University, rudakova1947@yandex.ru
Fatkabrarova Antonina Maratovna, Resident at day patient facility, Municipal clinical hospital of first aid named after G. A. Zacharyin (Penza), a_fatkabrarova@mail.ru
Bondarenko Lyudmila Alekseevna, Candidate of medical sciences, associate professor, sub-department of internal diseases, Medical Institute, Penza State University; head of cardiological unit № 2, Municipal clinical hospital of first aid named after G. A. Zacharyin (Penza), rudakova1947@yandex.ru
Belyaeva Yuliya Borisovna, Candidate of medical sciences, associate professor, sub-department of internal diseases, Medical Institute, Penza State University, verevayb@yandex.ru
Kazantsev Alexander Vasylyevich, Head of reanimation and intensive care unit № 2, Municipal clinical hospital of first aid named after G. A. Zacharyin (Penza), rudakova1947@yandex.ru

616–085+616–007.251+616.127–005.8

The article explores cardiac ruptures (CR) in the acute period of myocardial infarction (MI). The study is retrospective and was conducted in two stages. At the first stage, the authors measured the share of CR in the structure of in-hospital mor-tality for primary and repeated MI. At the second stage, we studied the impact of thrombolytic therapy (TLT) on frequency of CR in the acute period of MI and on changes in the mortality structure for this disease. Actilyse, metalyse and purolase were used as thrombolytic drugs. The researchers showed that TLT with these thrombolytics for MI does not significantly increase CR frequency, nor does it defi-nitely increase CR frequency in the mortality structure. It is presumed that, to a sig-nificant extent, late thrombolysis triggers CR.

myocardial infarction, thrombolytic therapy, cardiac ruptures.